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1

Synthesis of Plaunotol Derivatives and their Antibacterial Activities against Helicobacter pylori

Keiko Tago, Emiko Minami, Kayoko Masuda, Toshiyuki Akiyama, Hiroshi Kogen

Journal:

Bioorganic & Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 277 KB

english, 2001

2

Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline-2-methanol to 2,2,3-Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin

Mayuko Ori, Narihiro Toda, Kazuko Takami, Keiko Tago, Hiroshi Kogen

Journal:

Angewandte Chemie

Année:

2003

Langue:

english

Fichier:

PDF, 124 KB

english, 2003

3

Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline-2-methanol to 2,2,3-Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin

Mayuko Ori, Narihiro Toda, Kazuko Takami, Keiko Tago, Hiroshi Kogen

Journal:

Angewandte Chemie International Edition

Année:

2003

Langue:

english

Fichier:

PDF, 124 KB

english, 2003

4

ChemInform Abstract: A Highly Stereoselective Synthesis of Plaunotol and Its Thiourea Derivatives as Potent Antibacterial Agents Against Helicobacter pylori.

Hiroshi Kogen, Keiko Tago, Masami Arai, Emiko Minami, Kayoko Masuda, Toshiyuki Akiyama

Journal:

Année:

1999

Fichier:

PDF, 32 KB

1999

5

ChemInform Abstract: Alutacenoic Acids A and B, Rare Naturally Occurring Cyclopropenone Derivatives Isolated from Fungi: Potent Non-Peptide Factor XIIIa Inhibitors.

Hiroshi Kogen, Toshihiro Kiho, Keiko Tago, Shuichi Miyamoto, Tomoyuki Fujioka, Noriko Otsuka, Keiko Suzuki-Konagai, Takeshi Ogita

Journal:

Année:

2000

Fichier:

PDF, 37 KB

2000

6

ChemInform Abstract: Bis(2,2,2-trifluoroethyl)bromophosphonoacetate, a Novel HWE Reagent for the Preparation of (E)-α-Bromoacrylates: A General and Stereoselective Method for the Synthesis of Trisubstituted Alkenes.

Keiko Tago, Hiroshi Kogen

Journal:

Année:

2000

Fichier:

PDF, 36 KB

2000

7

ChemInform Abstract: A Practical Total Synthesis of Plaunotol via Highly Z-Selective Wittig Olefination of α-Acetal Ketones.

Keiko Tago, Masami Arai, Hiroshi Kogen

Journal:

Année:

2000

Fichier:

PDF, 32 KB

2000

8

ChemInform Abstract: A Highly Stereoselective Synthesis of (E)-α-Bromoacrylates.

Keiko Tago, Hiroshi Kogen

Journal:

Année:

2001

Fichier:

PDF, 35 KB

2001

9

ChemInform Abstract: Practical and Effective Total Synthesis of Plaunotol via Novel and Stereoselective Method for Construction of Tri-substituted Olefins

Keiko Tago, Hiroshi Kogen

Journal:

Année:

2002

Fichier:

PDF, 25 KB

2002

10

Total Synthesis of (+)-Benzastatin E via Diastereoselective Grignard Addition to 2-Acylindoline.

Narihiro Toda, Mayuko Ori, Kazuko Takami, Keiko Tago, Hiroshi Kogen

Journal:

Année:

2003

Fichier:

PDF, 5 KB

2003

11

Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline-2-methanol to 2,2,3-Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin.

Mayuko Ori, Narihiro Toda, Kazuko Takami, Keiko Tago, Hiroshi Kogen

Journal:

Année:

2003

Fichier:

PDF, 135 KB

2003

12

Stereospecific Synthesis of 2,2,3-Trisubstituted Tetrahydroquinolines: Application to the Total Syntheses of Benzastatin E and Natural Virantmycin.

Mayuko Ori, Narihiro Toda, Kazuko Takami, Keiko Tago, Hiroshi Kogen

Journal:

Année:

2005

Fichier:

PDF, 28 KB

2005

13

Stereospecific Synthesis of 2,2,3-Trisubstituted Tetrahydroquinolines: Application to the Total Syntheses of Benzastatin E and Natural Virantmycin.

Mayuko Ori, Narihiro Toda, Kazuko Takami, Keiko Tago, Hiroshi Kogen

Journal:

Année:

2005

Fichier:

PDF, 35 KB

2005

14

Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis

Tatsuo Tanimoto, Yoshio Tsujita, Kiyoshi Hamano, Hideyuki Haruyama, Takeshi Kinoshita, Tsuyoshi Hosoya, Satoru Kaneko, Keiko Tago, Hiroshi Kogen

Journal:

Tetrahedron Letters

Année:

1995

Langue:

english

Fichier:

PDF, 216 KB

english, 1995

15

A case of fatal drug intoxication showing a high-density duodenal content by postmortem computed tomography

Rie Sano, Keiko Takahashi, Yoshihiko Kominato, Takuya Araki, Koujiro Yamamoto, Hiroyuki Takei, Hidenori Otake, Sachiko Awata, Hisashi Akuzawa, Yoko Tago, Hideo Aoki

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 242 KB

english, 2011

16

Stereospecific synthesis of 2,2,3-trisubstituted tetrahydroquinolines: application to the total syntheses of benzastatin E and natural virantmycin

Mayuko Ori, Narihiro Toda, Kazuko Takami, Keiko Tago, Hiroshi Kogen

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 833 KB

english, 2005

17

A highly stereoselective synthesis of plaunotol and its thiourea derivatives as potent antibacterial agents against Helicobacter pylori

Hiroshi Kogen, Keiko Tago, Masami Arai, Emiko Minami, Kayoko Masuda, Toshiyuki Akiyama

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 244 KB

english, 1999

18

Design, synthesis and structure–Activity relationships of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Narihiro Toda, Keiko Tago, Shinji Marumoto, Kazuko Takami, Mayuko Ori, Naho Yamada, Kazuo Koyama, Shunji Naruto, Kazumi Abe, Reina Yamazaki, Takao Hara, Atsushi Aoyagi, Yasuyuki Abe, Tsugio Kaneko, Hi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 553 KB

english, 2003

19

Conformational analysis and docking study of potent factor XIIIa inhibitors having a cyclopropenone ring

Yoriko Iwata, Keiko Tago, Toshihiro Kiho, Hiroshi Kogen, Tomoyuki Fujioka, Noriko Otsuka, Keiko Suzuki-Konagai, Takeshi Ogita, Shuichi Miyamoto

Journal:

Journal of Molecular Graphics and Modelling

Année:

2000

Langue:

english

Fichier:

PDF, 8.24 MB

english, 2000

20

A Highly Stereoselective Synthesis of (E)-α-Bromoacrylates

Keiko Tago, Hiroshi Kogen

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 146 KB

english, 2000

21

Corrigendum to “A highly stereoselective synthesis of (E)-α-bromoacrylates”: [Tetrahedron 56 (2000) 8825]

Keiko Tago, Hiroshi Kogen

Journal:

Année:

2001

Fichier:

PDF, 26 KB

2001

22

A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Narihiro Toda, Keiko Tago, Shinji Marumoto, Kazuko Takami, Mayuko Ori, Naho Yamada, Kazuo Koyama, Shunji Naruto, Kazumi Abe, Reina Yamazaki, Takao Hara, Atsushi Aoyagi, Yasuyuki Abe, Tsugio Kaneko, Hi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 589 KB

english, 2003

23

Design and Synthesis of Dual Inhibitors of Acetylcholinesterase and Serotonin Transporter Targeting Potential Agents for Alzheimer's Disease

Kogen, Hiroshi, Toda, Narihiro, Tago, Keiko, Marumoto, Shinji, Takami, Kazuko, Ori, Mayuko, Yamada, Naho, Koyama, Kazuo, Naruto, Shunji, Abe, Kazumi, Yamazaki, Reina, Hara, Takao, Aoyagi, Atsushi, Abe

Journal:

Organic Letters

Année:

2002

Langue:

english

Fichier:

PDF, 205 KB

english, 2002

24

A practical total synthesis of plaunotol via highly Z-selective Wittig olefination of α-acetal ketones

Tago, Keiko, Arai, Masami, Kogen, Hiroshi

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

2000

Langue:

english

Fichier:

PDF, 150 KB

english, 2000

25

Alutacenoic Acids A and B, Rare Naturally Occurring Cyclopropenone Derivatives Isolated from Fungi: Potent Non-Peptide Factor XIIIa Inhibitors

Kogen, Hiroshi, Kiho, Toshihiro, Tago, Keiko, Miyamoto, Shuichi, Fujioka, Tomoyuki, Otsuka, Noriko, Suzuki-Konagai, Keiko, Ogita, Takeshi

Journal:

Journal of the American Chemical Society

Année:

2000

Langue:

english

Fichier:

PDF, 116 KB

english, 2000

26

Bis(2,2,2-trifluoroethyl)bromophosphonoacetate, a Novel HWE Reagent for the Preparation of ( E )-α-Bromoacrylates: A General and Stereoselective Method for the Synthesis of Trisubstituted Alkenes

Tago, Keiko, Kogen, Hiroshi

Journal:

Organic Letters

Année:

2000

Langue:

english

Fichier:

PDF, 105 KB

english, 2000

27

Total Synthesis of (+)-Benzastatin E via Diastereoselective Grignard Addition to 2-Acylindoline

Toda, Narihiro, Ori, Mayuko, Takami, Kazuko, Tago, Keiko, Kogen, Hiroshi

Journal:

Organic Letters

Année:

2003

Langue:

english

Fichier:

PDF, 86 KB

english, 2003

28

Versatile Synthon for Chirally β -Deuterated L -Amino Acids and Synthesis of (3 R )- and (3 S )-[3– 2 H 1 - l -Serine*

Maeda, Yutaka, Tago, Keiko, Eguchi, Tadashi, Kakinuma, Katsumi

Journal:

Bioscience Biotechnology and Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1996

29

A case of Guillain–Barré syndrome with meningeal irritation

Ashikari, Yuka, Kobayashi, Satoru, Tago, Akari, Yoneyama, Mizuki, Ito, Midori, Fukuda, Keiko, Mizuno, Yoshifumi, Tsunoda, Yuko, Shimizu, Seiki, Yokoi, Kyoko, Kamioka, Naomi, Hamajima, Naoki, Suzuki, S

Journal:

Brain and Development

Année:

2015

Langue:

english

Fichier:

PDF, 470 KB

english, 2015

30

Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophyllum commune. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities.

TANIMOTO, TATSUO, ONODERA, KAORI, HOSOYA, TSUYOSHI, TAKAMATSU, YASUYUKI, KINOSHITA, TAKESHI, TAGO, KEIKO, KOGEN, HIROSHI, FUJIOKA, TOMOYUKI, HAMANO, KIYOSHI, TSUJITA, YOSHIO

Journal:

The Journal of Antibiotics

Année:

1996

Langue:

english

Fichier:

PDF, 552 KB

english, 1996

31

Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophylllum commune. II. Structure Elucidation and Total Synthesis.

KOGEN, HIROSHI, TAGO, KEIKO, KANEKO, SATORU, HAMANO, KIYOSHI, ONODERA, KAORI, HARUYAMA, HIDEYUKI, MINAGAWA, KATSUHIRO, KINOSHITA, TAKESHI, ISHIKAWA, TOMIO, TANIMOTO, TATSUO, TSUJITA, YOSHIO

Journal:

The Journal of Antibiotics

Année:

1996

Langue:

english

Fichier:

PDF, 619 KB

english, 1996

32

Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease

Abe, Yasuyuki, Aoyagi, Atsushi, Hara, Takao, Abe, Kazumi, Yamazaki, Reina, Kumagae, Yoshihiro, Naruto, Shunji, Koyama, Kazuo, Marumoto, Shinji, Tago, Keiko, Toda, Narihiro, Takami, Kazuko, Yamada, Nah

Journal:

Journal of Pharmacological Sciences

Année:

2003

Langue:

english

Fichier:

PDF, 315 KB

english, 2003

33

Reply to the letter: A case of Guillain–Barré syndrome with meningeal irritation

Ashikari, Yuka, Kobayashi, Satoru, Tago, Akari, Yoneyama, Mizuki, Ito, Midori, Fukuda, Keiko, Mizuno, Yoshifumi, Tsunoda, Yuko, Shimizu, Seiki, Yokoi, Kyoko, Kamioka, Naomi, Hamajima, Naoki, Suzuki, S

Journal:

Brain and Development

Année:

2017

Langue:

english

Fichier:

PDF, 75 KB

english, 2017

34

A Case of Fatal Pulmonary Hypoplasia with Congenital Diaphragmatic Hernia, Thoracic Myelomeningocele, and Thoracic Dysplasia

Ito, Ai, Fujinaga, Hideshi, Matsui, Sachiko, Tago, Kumiko, Iwasaki, Yuka, Fujino, Shuhei, Nagasawa, Junko, Amari, Shoichiro, Kaneshige, Masao, Wada, Yuka, Takahashi, Shigehiro, Tsukamoto, Keiko, Miyaz

Journal:

American Journal of Perinatology Reports

Année:

2017

Langue:

english

Fichier:

PDF, 220 KB

english, 2017

35

Conformational Analysis and Docking Study of Potent Acetylcholinesterase Inhibitors Having a Benzylamine Moiety

Toda, Narihiro, Iwata, Yoriko, Tago, Keiko, Kogen, Hiroshi, Kaneko, Tsugio, Miyamoto, Shuichi

Journal:

Chem-Bio Informatics Journal

Année:

2003

Fichier:

PDF, 577 KB

2003

36

Discovery of novel pyrrole derivatives as potent agonists for the niacin receptor GPR109A

Miyazawa, Yuriko, Yamaguchi, Takahiro, Yamaguchi, Mitsuhiro, Tago, Keiko, Tamura, Akihiro, Sugiyama, Daisuke, Aburatani, Takahide, Nishizawa, Tomohiro, Kurikawa, Nobuya, Kono, Keita

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2020

Langue:

english

Fichier:

PDF, 618 KB

english, 2020